The Wii sequel to Big Brain Academy for Nintendo DS includes three multiplayer modes for up to eight players. Players also can exchange student-record books with other players over WiiConnect24 and compete against their save data.With 15 new activities that challenge the brain in single-player Test and Practice modes, Big Brain Academy: Wii Degree sees how players measure up in five categories: Identify Memorize, Analyse, Compute and Visualize.All activities are designed around the Wii Remote's pointer. Players can play solo with one Wii Remote, or pass it around like a relay baton in group competitions.

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